By L. Qin, Harry K. Genant, J.F. Griffith, K.S. Leung
This publication offers a standpoint at the present prestige of bioimaging applied sciences constructed to evaluate the standard of musculoskeletal tissue with an emphasis on bone and cartilage. It bargains reviews of scaffold biomaterials constructed for boosting the fix of musculoskeletal tissues. those bioimaging concepts comprise micro-CT, nano-CT, pQCT/QCT, MRI, and ultrasound, which offer not just 2-D and 3-D pictures of the similar organs or tissues, but in addition quantifications of the appropriate parameters. the development bioimaging applied sciences built for the above functions also are prolonged through incorporating imaging contrast-enhancement fabrics. hence, this e-book will supply a different platform for multidisciplinary collaborations in schooling and joint R&D between a number of professions, together with biomedical engineering, biomaterials, and uncomplicated and medical drugs.
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Additional info for Advanced Bioimaging Technologies in Assessment of the Quality of Bone and Scaffold Materials: Techniques and Applications
Technically, the challenges reﬂect the balances and trade-oﬀs between spatial resolution, sample size, signal-to-noise ratio, radiation exposure, and acquisition time, or between the complexity and expense of the imaging technologies vs their availability and accessibility. Clinically, the challenges for bone imaging include balancing the advantages of standard BMD information vs the more complex architectural features of bone, or the deeper research requirements of the laboratory vs the broader needs of clinical practice.
With the aid of X-ray and CT-based non-invasive imaging techniques, the skeletal geometry data from a normal subject or a patient can be used for model extraction using more advanced image-processing algorithms. For the nonosseous connective tissues interacting with the bone, MRI technique is strongly indicated; however, during activities, the musculoskeletal system is constantly changing its conﬁguration and sometimes these tissues may involve subtle deformation under large loads. To reconstruct these models incorporating body and limb movement and tissue deformation including the micro-motion of the internal devices or prostheses in the body relative to the bone where they are anchored presents new challenges to current state-of-the-art bio-imaging.
Twenty-node reduced-integration brick elements were used in each FEM model.
Advanced Bioimaging Technologies in Assessment of the Quality of Bone and Scaffold Materials: Techniques and Applications by L. Qin, Harry K. Genant, J.F. Griffith, K.S. Leung